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These keywords were added by machine and not by the authors. Cutaneous lupus erythematosus: new insights into pathogenesis and therapeutic strategies.Subacute Cutaneous Lupus Erythematosus.

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Drug-induced lupus.Cutaneous lupus erythematosus (CLE) is an autoimmune disease that can present as an isolated skin disease or as a manifestation within the spectrum of systemic lupus erythematosus. These lesions do not cause scarring but may cause skin discoloration. Subacute cutaneous lupus erythematosus refers to skin lesions that appear on parts of the body that have exposure to the sun. About 85% of people with subacute cutaneous lupus are extremely photosensitive. Subacute cutaneous lupus erythematosus pictures are available at the following websites:. Papulosquamous, or scaly bumps, may also appear. All three types produce some form of rash or discoloration on the surface of the skin subacute lupus erythematosus, however, is. Subacute cutaneous lupus erythematosus, a lesser form of lupus that does not necessarily lead to systemic (whole body) tissue damage, is one of three types of autoimmune skin disorders caused by lupus antibodies. Wollina U et al (1989) On the spectrum of dermatological manifestations in patients with subacute cutaneous lupus erythematosus and their nosological significance.

Tebbe B et al (1994) Course and prognosis of subacute cutaneous lupus erythematosus.

The subacute cutaneous lupus will have symptoms that are visible on the skin: Lesions that are present on the arms, neck, shoulders or trunk in rare cases, the scaly patches may also affect the face The exact causes of subacute cutaneous lupus are unknown, but many suspect genetic factors. More than four American Rheumatism Association (ARA) criteria for systemic lupus erythematosus (SLE) are found in a proportion of patients diagnosed as having SCLE thus such cases could be classified as SLE.

Background: The nosologic position of subacute cutaneous lupus erythematosus (SCLE) is controversial. Like DLE, the individual lesions of SCLE may last for months in contrast to DLE, they heal.

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However, SCLE can be associated with the full spectrum of LE-associated phenomena (Table 17.5 ). Subacute cutaneous lupus erythematosus (SCLE) encompasses the clinical spectrum of cutaneous LE between the chronic, destructive DLE and the erythema of ALE. This clinically distinct form of cutaneous LE has not previously. We have characterized the clinical and laboratory features of 27 patients who had in common a recurring, superficial, nonscarring type of cutaneous lupus erythematosus (LE) that occurred in a characteristic distribution (subacute cutaneous lupus erythematosus ).